The cold biological truth is that sex changes are impossible. Every single cell of the human body remains coded with one's birth gender for life. Intersex ambiguities can occur, but they are developmental anomalies that represent a tiny proportion of all human births.In a democracy, everyone, no matter how nonconformist or eccentric, should be free from harassment and abuse. But at the same time, no one deserves special rights, protections, or privileges on the basis of their eccentricity. The categories "trans-man" and "trans-woman" are highly accurate and deserving of respect. But like Germaine Greer and Sheila Jeffreys, I reject state-sponsored coercion to call someone a "woman" or a "man" simply on the basis of his or her subjective feeling about it. We may well take the path of good will and defer to courtesy on such occasions, but it is our choice alone.

A wide-ranging interview. Source: Camille Paglia: On Trump, Democrats, Transgenderism, and Islamist Terror | The Weekly Standard